Largest Lawsuit Settlement in History – A Settlement Agreement of a whoping $206 Billion!. For the full article, be sure to check out our legal partners: Houston Texas Accident Lawyer The ‘Master Settlement Agreement (MSA)’, as it came to be known, saw four of the largest companies in the United States – Philip Morris Inc., R.J. Reynolds, Brown & Williamson, and Lorillard – agree to pay $206 billion over 25 years.